PT-141 (Bremelanotide)

PT-141 (Bremelanotide)

Catalog strength: 10mg/3ml

Research Overview

Overview: PT-141 (Bremelanotide) is a synthetic peptide analog derived from melanocortin hormones. It interacts with the melanocortin receptor family-particularly MC3R and MC4R-both found within the central nervous system. Research has focused on its ability to influence neural pathways related to motivation, behavior, and neuroendocrine signaling. Unlike compounds acting on vascular nitric-oxide pathways, PT-141 works through central melanocortin receptors, a key distinction noted in scientific literature. Mechanism of Action (Summaries of published research – not effects of this product.) MC3R/MC4R Activation: Engages melanocortin receptors in the hypothalamus, influencing neurobehavioral responses. Non-Vascular Pathway: Research shows effects independent of nitric-oxide-mediated mechanisms. Central Neuroregulation: Alters neural circuits involved in behavioral and autonomic responses. Pharmacokinetics (Research findings, not product claims.) Rapid absorption in studies involving subcutaneous administration (approx. 30 minutes to measurable activity).

Research Findings

Behavioral Response: Studies report centrally mediated changes in motivation and neurobehavioral arousal via MC3R/MC4R activation.

CNS-Driven Effects: Research indicates modulation of neural pathways associated with desire, reward, and behavioral signaling.

Non-NO Mechanism: Reported activity in individuals who do not respond to nitric-oxide-based agents, highlighting a unique CNS-driven pathway.

CAS number: 189691-06-3

Molar mass: 1025.2 g/mol

RESEARCH USE ONLY – NOT FOR HUMAN OR VETERINARY USE.

This product is offered strictly as a laboratory research material for qualified researchers and educational or analytical use. It is not a drug, food, dietary supplement, cosmetic, medical device, or consumer product. It is not intended for ingestion, injection, inhalation, topical application, compounding, prescribing, dispensing, administration, or any other use in humans or animals.

This product has not been approved by the U.S. Food and Drug Administration. It is not intended to diagnose, treat, cure, mitigate, or prevent any disease or medical condition. Statements describing mechanisms, pathways, observations, or potential benefits summarize the research context presented in the source catalog and do not constitute medical advice, therapeutic claims, instructions for use, or evidence of safety or efficacy in humans.

The purchaser is solely responsible for verifying that acquisition, possession, handling, storage, research, transfer, and disposal comply with all applicable federal, state, and local laws, institutional requirements, and laboratory safety standards. Sale may be restricted to appropriately qualified research entities. By purchasing, the purchaser represents that the material will be used only for lawful, non-clinical research and will not be resold or supplied for human or veterinary administration.