NAD+

NAD+

Catalog strength: 1000mg/10ml

Research Overview

Overview: NAD+ (nicotinamide adenine dinucleotide) is a coenzyme present in all living cells and is essential for supporting a wide range of metabolic and redox reactions. It functions as a central electron carrier in energy metabolism and plays a key role in maintaining cellular homeostasis in laboratory systems. NAD+ also serves as a substrate for various enzyme families-including sirtuins, PARPs, and CD38-which regulate genomic stability, chromatin structure, cellular stress responses, and protein modification.(NAD+ concentrations are known to fluctuate under metabolic stress, aging models, and oxidative conditions, which has led to its use in research exploring cellular resilience mechanisms. Energy Metabolism In cell-based and animal studies, NAD+ participates in: Mitochondrial electron transport ATP production Redox cycling across metabolic pathways Genome Stability & Enzyme Activity NAD+ functions as a required substrate for: PARP enzymes involved in DNA-damage response Sirtuin deacetylases linked to chromatin structure and stress signaling Cellular Stress Response Models suggest that changes in NAD+ availability may influence: Oxidative-stress signaling Protein-folding pathways Cellular adaptation to energy imbalance

CAS number: 53-84-9

Molar mass: 663.43 g/mol

RESEARCH USE ONLY – NOT FOR HUMAN OR VETERINARY USE.

This product is offered strictly as a laboratory research material for qualified researchers and educational or analytical use. It is not a drug, food, dietary supplement, cosmetic, medical device, or consumer product. It is not intended for ingestion, injection, inhalation, topical application, compounding, prescribing, dispensing, administration, or any other use in humans or animals.

This product has not been approved by the U.S. Food and Drug Administration. It is not intended to diagnose, treat, cure, mitigate, or prevent any disease or medical condition. Statements describing mechanisms, pathways, observations, or potential benefits summarize the research context presented in the source catalog and do not constitute medical advice, therapeutic claims, instructions for use, or evidence of safety or efficacy in humans.

The purchaser is solely responsible for verifying that acquisition, possession, handling, storage, research, transfer, and disposal comply with all applicable federal, state, and local laws, institutional requirements, and laboratory safety standards. Sale may be restricted to appropriately qualified research entities. By purchasing, the purchaser represents that the material will be used only for lawful, non-clinical research and will not be resold or supplied for human or veterinary administration.