Mazdutide

Mazdutide

Catalog strength: 10mg/3ml

Research Overview

It has been approved in China (June 2025) for chronic weight management. (Research suggests that dual-agonist activity may influence appetite regulation, glucose metabolism, and energy expenditure. Mechanistic Background GLP-1 Receptor Activation Supports glucose-dependent insulin secretion Modulates appetite signals in the central nervous system Glucagon Receptor Activation May increase energy expenditure in research settings Enhances lipid metabolism pathways Pharmacokinetics Extended half-life: 174-1075 hours, attributed to fatty-acid conjugation and albumin binding Enables once-weekly administration

Research Findings

*All statements reflect findings from published studies; not intended as medical claims

China) Glycemic Measures: Studies document HbA1c improvements of approximately 1.41-2.23%, with a high percentage achieving HbA1c <7%.

Cardiometabolic Markers: Research shows possible reductions in systolic blood pressure (~7.57-9.21 mmHg) and triglycerides (~43.29%).

Visceral Adiposity: Imaging studies suggest preferential decreases in visceral adipose tissue.

Energy-Balance Mechanisms: Mazdutide's combined agonism may influence both anabolic and catabolic pathways relevant to metabolic regulation.

Insulin Sensitivity Indicators: Observational data include reductions in fasting insulin, HOMA-IR, and uric acid.

CAS number: 2448764-54-9

Molar mass: 5217.89 g/mol

RESEARCH USE ONLY – NOT FOR HUMAN OR VETERINARY USE.

This product is offered strictly as a laboratory research material for qualified researchers and educational or analytical use. It is not a drug, food, dietary supplement, cosmetic, medical device, or consumer product. It is not intended for ingestion, injection, inhalation, topical application, compounding, prescribing, dispensing, administration, or any other use in humans or animals.

This product has not been approved by the U.S. Food and Drug Administration. It is not intended to diagnose, treat, cure, mitigate, or prevent any disease or medical condition. Statements describing mechanisms, pathways, observations, or potential benefits summarize the research context presented in the source catalog and do not constitute medical advice, therapeutic claims, instructions for use, or evidence of safety or efficacy in humans.

The purchaser is solely responsible for verifying that acquisition, possession, handling, storage, research, transfer, and disposal comply with all applicable federal, state, and local laws, institutional requirements, and laboratory safety standards. Sale may be restricted to appropriately qualified research entities. By purchasing, the purchaser represents that the material will be used only for lawful, non-clinical research and will not be resold or supplied for human or veterinary administration.