Kisspeptin

Kisspeptin

Catalog strength: 10mg/3ml

Research Overview

Overview: Kisspeptin is a family of neuropeptides widely used in laboratory environments to study regulation of the hypothalamic-pituitary-gonadal (HPG) axis. It binds to KISS1R (GPR54) receptors on hypothalamic GnRH neurons, initiating the G±q/11-PLC² signaling cascade, which triggers GnRH release. Forms Commonly Studied Kisspeptin-54 (full-length peptide; longer half-life) Kisspeptin-10 (shorter fragment; rapid onset) Research interest includes pharmacokinetics, receptor activity, and downstream signaling effects in both in vitro and animal models.

Research Findings

Neuroendocrine Regulation GnRH Pathway Activation: Kisspeptin is a key upstream regulator of GnRH neurons and is widely used to study pulsatile GnRH release (Animal Study).

HPG Axis Modeling LH/FSH Release: Kisspeptin stimulation of KISS1R is used to evaluate LH and FSH secretion patterns and downstream reproductive signaling (Lab Study).

Puberty-Onset Mechanisms Developmental Timing Models: Kisspeptin is used to investigate the timing and regulation of pubertal development and neuroendocrine maturation (Animal/Translational Research).

CAS number: 374675-21-5

Molar mass: 1302.46 g/mol

RESEARCH USE ONLY – NOT FOR HUMAN OR VETERINARY USE.

This product is offered strictly as a laboratory research material for qualified researchers and educational or analytical use. It is not a drug, food, dietary supplement, cosmetic, medical device, or consumer product. It is not intended for ingestion, injection, inhalation, topical application, compounding, prescribing, dispensing, administration, or any other use in humans or animals.

This product has not been approved by the U.S. Food and Drug Administration. It is not intended to diagnose, treat, cure, mitigate, or prevent any disease or medical condition. Statements describing mechanisms, pathways, observations, or potential benefits summarize the research context presented in the source catalog and do not constitute medical advice, therapeutic claims, instructions for use, or evidence of safety or efficacy in humans.

The purchaser is solely responsible for verifying that acquisition, possession, handling, storage, research, transfer, and disposal comply with all applicable federal, state, and local laws, institutional requirements, and laboratory safety standards. Sale may be restricted to appropriately qualified research entities. By purchasing, the purchaser represents that the material will be used only for lawful, non-clinical research and will not be resold or supplied for human or veterinary administration.